Changes in serum levels of the variables under study. Values are expressed as mean (SD)
| Baseline | 2 Weeks | 3 Months | 6 Months | |
|---|---|---|---|---|
| Wilcoxon’s test for paired data. *p<0.05; **p<0.01; ***p<0.001. n=9. | ||||
| Homocysteine (normal range <15 μmol/l) | ||||
| μmol/l | 13.1 (3.5) | 11.0 (3.6)*** | 10.6 (2.7)*** | 9.6 (2.7)*** |
| Δ % | −16.9 | −18.3 | −26.0 | |
| Creatinine (normal range 50–110 μmol/l) | ||||
| μmol/l | 58 (18) | 64 (9) | 65 (18) | 65 (18) |
| Δ % | +8.6 | +9.1 | +8.9 | |
| Folate (normal range 3–17 ng/ml) | ||||
| ng/ml | 6.3 (3.3) | 6.7 (5.0) | 6.8 (3.0) | 6.7 (2.0) |
| Δ % | +6.0 | +6.4 | +5.8 | |
| B12 (normal range 200–950 pg/ml) | ||||
| pg/ml | 498.4 (155) | 478.2 (142) | 484.5 (231) | 498.9 (218) |
| Δ % | −3.7 | −3.1 | +1.2 | |
| B6 (normal range 4.3–17.9 ng/ml) | ||||
| ng/ml | 5.7 (2.8) | 6.2 (3.6) | 5.7 (2.4) | 5.7 (2.5) |
| Δ % | +8.4 | +0.3 | −0.1 | |
| Betaine (normal range 20–144 μmol/l) | ||||
| μmol/l | 49.7 (21) | 42.7 (24) | 38.1 (20)* | 35.0 (18)** |
| Δ % | −11.5 | −19.1 | −25.3 | |
| CRP (normal value <5 mg/l) | ||||
| mg/l | 35.7 (15) | 20.9 (13)* | 23.9 (10) | 24.2 (11) |
| Δ % | −42.3 | −29.2 | −30.3 | |