Table 2

Immunological findings, treatment, and outcome

PatientsANA titreSpecificityG-CSF level (ng/l)HLA-DRTreatmentOutcome (neutrophil count)
ANA, antinuclear antibodies; NI, not identified; ND, not done; G-CSF, granulocyte-colony stimulating factor; MTX, methotrexate; IVIg, intravenous immunoglobulins.
180NI1204–16/1–5Steroids
Steroids + MTX
No response
Transient recovery
280Ro/SSA564–13/52–53Recovery during pregnancy, then relapse
380NIND15–13Recovery during pregnancy, then relapse
4160NINDPersistent severe neutropenia
5640Ro/SSAND3-3Steroids
Steroids + IVIg
No response
Durable recovery
6320NI23Steroids
Steroids + MTX
No response
Partial recovery
71280Ro/SSA
La/SSB
123–4/52–53Persistent severe neutropenia