Progression of Sharp scores from baseline to three and five years in patients with or without rheumatoid factor and with or without anticitrullinated proteins/peptides antibodies
| 3 Years | 5 Years | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean total score | Erosions | Joint space narrowing | Mean total score | Erosions | Joint spacing narrowing | |||||||
| *Only p values <0.05 are reported. CCP, cyclic citrullinated peptides; APF, antiperinuclear Factor; AKA, antikeratin antibody. | ||||||||||||
| RF+CCP+ | 6.4 | 3.3 | 2.9 | 14.5 | 5.3 | 9.1 | ||||||
| }p = 0.047* | }p= 0.002 | }p = 0.0005 | }p = 0.02 | |||||||||
| RF+CCP- | 5.8 | 3.0 | 2.6 | 7.8 | 3.0 | 4.7 | ||||||
| }p = 0.01 | }p = 0.006 | }p = 0.044 | ||||||||||
| RF-CCP+ | 11.5 | 6.7 | 4.6 | 19.8 | 8.3 | 11.5 | ||||||
| RF- CCP- | 7.8 | 5.2 | 2.5 | 10.6 | 4.3 | 6.3 | ||||||
| RF+ APF+ | 7.9 | 4.2 | 3.8 | 15.4 | 5.7 | 9.7 | ||||||
| }p = 0.009 | }p= 0.02 | }p = 0.03 | }p= 0.003 | }p = 0.01 | }p = 0.006 | |||||||
| RF+ APF- | 4.2 | 2.3 | 1.7 | 8.7 | 3.4 | 5.4 | ||||||
| }p = 0.04 | ||||||||||||
| RF-APF+ | 10.8 | 5.7 | 5.0 | 18.6 | 6.3 | 11.2 | ||||||
| RF-APF- | 7.8 | 5.6 | 2.1 | 14.0 | 6.3 | 7.4 | ||||||