Sharp scores (absolute values) at baseline and after three and five years in patients with and without anti-CCP ELISA antibodies and with and without APF IIF
| Statistical difference between positive and negative for: | |||
|---|---|---|---|
| Follow up | Sharp score | Anti-CCP ELISA | APF IIF |
| Baseline | Total damage | 0.0006 | 0.09 |
| Erosions | 0.0004 | 0.051 | |
| Joint space narrowing | 0.032 | 0.14 | |
| 3 years | Total damage | 0.007 | 0.009 |
| Erosions | 0.015 | 0.058 | |
| Joint space narrowing | 0.066 | 0.009 | |
| 5 years | Total damage | 0.001 | 0.008 |
| Erosions | <0.0001 | 0.004 | |
| Joint space narrowing | 0.029 | 0.010 | |