Cytokine | Mouse strain | Sex | Age (months) | % Positive chondrocytes (medians) | |
---|---|---|---|---|---|
Medial | Lateral | ||||
The total numbers of articular chondrocytes in each thin section were determined for the medial and the lateral sides of the joints and the percentages of positively stained chondrocytes and corresponding medians were calculated. | |||||
IL1β | STR/ort | Male | 2.0 | 5.0 | 2.5 |
3.5 | 2.0 | 7.6 | |||
10.5 | 0 | 0.3 | |||
Female | 2.0 | 5.8 | 27.3 | ||
3.5 | 5.3 | 19.6 | |||
10.5 | 0 | 4.2 | |||
BALB/c | Male | 2.0 | 3.9 | 3.8 | |
Female | 2.0 | 10.1 | 8.6 | ||
IL4 | STR/ort | Male | 2.0 | 0 | 0 |
3.5 | 6.1 | 7.1 | |||
10.5 | 0 | 0 | |||
Female | 2.0 | 3.4 | 27.9 | ||
3.5 | 0 | 2.1 | |||
10.5 | 0 | 0 | |||
BALB/c | Male | 2.0 | 2.8 | 4.1 | |
Female | 2.0 | 0 | 0 | ||
TGFβ1 | STR/ort | Male | 2.0 | 0 | 0 |
3.5 | 0 | 0 | |||
10.5 | 0 | 0 | |||
Female | 2.0 | 4.4 | 23.1 | ||
3.5 | 6.2 | 10.9 | |||
10.5 | 0 | 0.7 | |||
BALB/c | Male | 2.0 | 5.4 | 3.9 | |
Female | 2.0 | 14.2 | 24.0 | ||
IL6 | STR/ort | Male | 2.0 | 3.4 | 4.1 |
3.5 | 0.6 | 3.4 | |||
10.5 | 0 | 0 | |||
Female | 2.0 | 0 | 11.2 | ||
3.5 | 1.0 | 1.9 | |||
10.5 | 0 | 0 | |||
BALB/c | Male | 2.0 | 1.4 | 4.0 | |
Female | 2.0 | 0 | 0 | ||
TNFα | STR/ort | Male | 2.0 | 0 | 0.9 |
3.5 | 0 | 8.1 | |||
10.5 | 0 | 0.3 | |||
Female | 2.0 | 0 | 9.4 | ||
3.5 | 0.4 | 0 | |||
10.5 | 0 | 1.4 | |||
BALB/c | Male | 2.0 | 5.0 | 2.6 | |
Female | 2.0 | 1.5 | 1.4 | ||
IL10 | STR/ort | Male | 2.0 | 1.2 | 3.9 |
3.5 | 3.2 | 5.0 | |||
10.5 | 0 | 0 | |||
Female | 2.0 | 6.3 | 7.3 | ||
3.5 | 4.7 | 5.4 | |||
10.5 | 0 | 1.3 | |||
BALB/c | Male | 2.0 | 0.7 | 2.1 | |
Female | 2.0 | 0.3 | 1.4 |