Table 2

Correlations (rs) between pro-MMP and activated MMP levels and CRP and DAS in the patients with RA at baseline, 1 and 2 years

CRPDAS
*p<0.05;
†p<0.005 (Spearman’s rs).
CRP, C reactive protein; MMP, matrix metalloproteinase, DAS, disease activity score; α2M, α2 macroglobulin.
Baseline
    Pro-MMP-30.33†0.28*
    Pro-MMP-80.32†−0.03
    Pro-MMP-90.04−0.18
    MMP activity in α2M0.36†0.28*
One year
    Pro-MMP-30.70†0.38*
    Pro-MMP-80.28*−0.04
    Pro-MMP-90.12−0.03
    MMP activity in α2M0.54†0.41†
Two years
    Pro-MMP-30.52†0.22
    Pro-MMP-80.14−0.12
    Pro-MMP-9−0.03−0.13
    MMP activity in α2M0.46†0.33*