Group A (positive retinal disease) (n=10) | Group B (negative retinal disease) (n=19) | p Value | |
---|---|---|---|
BP, blood pressure; ESR, erythrocyte sedimentation rate; | |||
*Prostaglandin: alprostadil or beraprost sodium or cilostazol. | |||
Background | |||
Male/female | 1/10 | 2/17 | >0.5 |
Age at examination (years) | 65.0 (5.7) | 55.0 (12.1) | <0.03 |
Age at onset of SSc (years) | 53.0 (10.0) | 41.0 (14.0) | 0.03 |
Disease duration (years) | 13.2 (7.6) | 13.9 (10.1) | 0.85 |
General findings | |||
Disease type (limited/diffuse) | 7/3 | 14/5 | >0.5 |
(% limited type) | (70) | (74) | |
Systolic BP (mm Hg) | 132 (21) | 112 (19) | 0.03 |
Diastolic BP (mm Hg) | 77 (10) | 72 (9) | 0.16 |
Raynaud’s phenomenon | 90 | 100 | 0.34 |
Skin ulcer | 60 | 63 | >0.5 |
Pulmonary fibrosis | 30 | 58 | >0.5 |
Laboratory data | |||
ESR (mm/1st h) | 32 (23) | 22 (20) | 0.22 |
Antinuclear antibodies (+) | 90 | 63 | 0.26 |
Rheumatoid factor (+) | 60 | 52 | >0.5 |
Anticentromere antibodies (+) | 30 | 11 | 0.21 |
Antitopoisomerase I antibodies (+) | 50 | 35 | 0.45 |
Anti-RNP antibodies (+) | 0 | 6 | >0.5 |
Drugs | |||
Prostaglandin* | 50 | 47 | >0.5 |
d-Penicillamine | 100 | 90 | >0.5 |
Corticosteroid | 30 | 32 | >0.5 |