Table 2

Total number adverse events related to study drug

Group
Kind of adverse eventCsA plus MTXCsA
A period with >30% raised serum creatinine4742
A period with hypertension3838
Gastric intestinal complaints2826
Hypertrichosis1319
Headache1113
Raised serum potassium104
Liver enzyme disturbances77
Paraesthesias67
Gingivitis58
Fluid retention53
Tremor42
Metrorrhagia31
Fatigue13
Others1919
Total197192