Table 2

Serum levels and status of anti-CCP, IgM RF, IgA RF, IgG RF, APF, and AKA in patients who showed any radiographic progression in Larsen score (radiographic progressors) and in those who did not have any increase in Larsen score after two years’ follow up (radiographic non-progressors). Results are shown as No (%) unless otherwise stated

Radiographic progressors
(n=49)
Radiographic non-progressors (n=55)Significance (p value)OR (95% CI)
Anti-CCP+32 (65)12 (22)<0.0016.7 (2.8 to 16.1)
IgM RF+29 (59)21 (38)0.052.4 (1.1 to 5.7)
IgA RF+30 (61)17 (30)0.0033.5 (1.6 to 7.9)
IgG RF+27 (55)11 (20)<0.0014.9 (2.1 to 11.7)
APF+25 (51)13 (24)0.0053.4 (1.5 to 7.8)
AKA+29 (59)10 (18)<0.0016.5 (2.7 to 15.9)
Anti-CCP+ and IgM RF+23 (47)7 (13)0.0024.8 (1.8 to 12.8)
Anti-CCP+ and/or IgM RF+39 (80)25 (45)<0.0014.7 (2.0 to 11.2)
Anti-CCP (units), mean (SD)217.2 (248)72.7 (141)<0.001
IgM RF (index), mean (SD)3.7 (3.1)2.2 (2.1)0.002
IgA RF (index), mean (SD)3.2 (2.7)2.0 (2.5)<0.001
IgG RF (index), mean (SD)3.5 (3.0)1.9 (2.5)<0.001