AKA, APF, anti-CCP antibodies, and RF isotypes determined at the presenting visit of patients with early RA with erosive and non-erosive disease. Results are shown as No (%) unless otherwise stated
| All early RA (n=104) | Erosive RA (n=67) | Non-erosive RA (n=37) | Difference erosive v non-erosive (p value) | |
|---|---|---|---|---|
| AKA+ | 39 (38) | 33 (49) | 6 (16) | 0.001 |
| APF+ | 38 (37) | 30 (45) | 8 (22) | 0.021 |
| Anti-CCP+ | 44 (42) | 36 (54) | 8 (22) | 0.002 |
| IgM RF+ | 50 (48) | 39 (58) | 11 (30) | 0.008 |
| IgA RF+ | 47 (45) | 36 (54) | 11 (30) | 0.024 |
| IgG RF+ | 38 (37) | 30 (45) | 8 (22) | 0.021 |
| Anti-CCP (units), mean (SD) | 140.8 (211) | 159.1 (224) | 85.8 (165) | 0.007 |
| IgM RF (index), mean (SD) | 2.9 (2.7) | 3.3 (2.8) | 2.0 (2.2) | 0.003 |
| IgA RF (index), mean (SD) | 2.6 (2.7) | 2.9 (2.6) | 1.9 (2.8) | <0.001 |
| IgG RF (index), mean (SD) | 2.7 (2.8) | 3.0 (2.8) | 2.1 (2.8) | 0.013 |
| Anti-CCP+ and/or IgM RF+ | 64 (62) | 50 (75) | 14 (38) | <0.001 |