Table 3

Univariate analysis of risk factors for atherosclerosis in 78 patients with SLE: continuous variables (mean (SD))* in patients with (yes) and without (no) carotid lesions. Only significant results are reported

PlaqueThickened intima
Risk factorsYes (n=13)No (n=65)p ValueYes (n=22)No (n=56)p Value
BMI, body mass index; BP, blood pressure; PRD, prednisone cumulative dosage.
*For all modifiable risk factors we considered the mean values of the measurements obtained at each evaluation during follow up (see methods).
†For age, BMI, systolic BP, diastolic BP, smoking, and hypercholesterolaemia.
Age (years)45.7 (9.9)35.3 (8.8)<0.000543.3 (10.6)34.6 (8.2)<0.0005
BMI (kg/m2)25.0 (3.3)23.2 (3.3)NS24.9 (3.5)22.9 (3.5)0.037
Total cholesterol (mmol/l)6.1 (1.3)5.0 (1.0)0.0015.8 (1.4)4.9 (0.9)0.002
Triglycerides (mmol/l)1.8 (1.2)1.4 (0.7)NS1.9 (1.1)1.4 (0.5)0.01
Systolic BP (mm Hg)138 (16.7)124.5 (12.3)0.001133.8 (16.1)123.9 (12.1)0.004
Diastolic BP (mm Hg)86.9 (7.2)80.3 (9.0)0.01786.3 (8.1)79.5 (8.7)0.002
PRD not adjusted (g)46.2 (24.2)27.9 (15.3)0.00138.0 (23.0)28.1 (15.4)0.031
PRD Adjusted† (g)45.2 (5.0)28.1 (2.09)0.00336.1 (4.05)28.9 (2.4)NS