Table 1

Clinical and ultrasonographic data during the observation period

Baseline
Median (range)
2 Weeks
Median (range)
1 Year
Median (range)
VAS, visual analogue scale; HAQ, Health Assessment Questionnaire; ESR, erythrocyte sedimentation rate; ROI, region of interest; RI, resistance index.
Change in comparison with baseline: *p<0.05; **p<0.01.
VAS (mm)66 (10–91)33 (8–91)*31 (10–70)**
HAQ23 (1–43)19 (0–40)*18 (1–37)*
Morning stiffness (min)75 (0–150)30 (0–120)*45 (0–120)*
ESR (mm/1st h)40 (6–95)21 (4–65)*32 (8–83)
Doctor’s global assessment6 (1–9)4 (1–8)*4 (1–7)*
Patient’s global assessment7 (1–9)4 (1–9)*4 (1–9)*
Swelling of the target joint2 (1–3)1 (1–3)*2 (0–2)
Synovial thickness (cm)0.59 (0.24–1.09)0.63 (0.21–0.95)0.54 (0.27–0.68)
Coloured pixels per ROI0.10 (0.00–0.43)0.04 (0.0–0.21)**0.11 (0.0–0.22)
Mean RI0.82 (0.61–1.29)1.06 (0.68–1.30)**1.01 (0.76–1.37)