Table 2

Results of the seven patients who completed the n of 1 trials: outcome measures, recommendations, drugs after three months, and confidence

Patient NoJointMost important complaintFunction testMedian difference N − P* (median N, median P)†Proportion of pairs N>P for the primary outcome measuresRecommendationDrug treatment after 3 monthsδ Confidence GP (choice before, choice after)‡
Total diary scoreIndividual main complaintPainSatisfactionFunction test (seconds)Total diary scoreIndividual main complaintPain
H, hip; K, knee; W, walking; ST, walking stairs; S, sitting and standing up; N, NSAID; P, paracetamol.
*Negative scores favour NSAIDs; †scores range between 0 = no complaints and 6 = unbearable complaints for the total diary score and the individual main complaint, between 0 = no pain and 10 = very severe pain for the intensity of pain, and between 0 = very satisfied and 6 = very dissatisfied for the satisfaction with drugs; ‡confidence of general practitioner in the preferred drug at the start of the study minus at the end of the study. Positive scores indicate that the general practitioner is more certain after the study; §walking upstairs; walking downstairs; ¶data of only four pairs could be compared.
1HPain during standing up from a chair or couchW0 (3, 3)0 (3, 3)−1 (6, 7)0 (2, 2)0.5 (10.5, 10.6)1/51/53/5PN0 (N, P)
3KPain during walkingW−0.5 (3, 3.5)0 (4, 4)0 (6, 6)0 (3, 3)0 (12.0, 11.7)3/50/50/5PN and P1 (N, P)
4Kpain during walkingW0 (2.5, 2.5)0 (3, 3)0 (7, 7)0 (3, 2)−0.7 (16.0, 16.9)2/52/52/5PN0 (N, P)
5KPain during sleepingW0 (0, 0)0 (0, 0)0 (0, 0)0 (0, 0)0.2 (6.8, 6.6)0/50/52/5PP2 (N, P)
6KPain during standing up from the toiletST−1 (3, 4)−1 (3, 4)0 (7, 8)0 (3, 5)−0.8; −2.0 (12.2, 13.2; 17.7, 19.4)§4/54/52/5NN2 (N, N)
KPain during standing up from a chairS−1 (1, 2)−0.5 (1, 2)−3 (3, 5.5)0.5 (1.5, 1)0.8 (18.6, 18.9)3/42/43/4PN1 (P, P)
9KPain during standingW0 (3, 3)0 (3, 3)−1 (6, 7)0 (2, 2)−3.6 (20.2, 22.7)1/51/53/5PN (and P)0 (P, P)