Quantification of the expression of p53 in rheumatoid arthritis and control tissues by immunohistochemistry using a scoring system from 0 to IV*
| 0 | I | II | III | IV | Mean (%) | Range | SD | |
|---|---|---|---|---|---|---|---|---|
| *Percentage of p53 positive cells: 0 = 0%; I = <1%; II = 1–5%; III = >5–20%; IV = >20%. | ||||||||
| Rheumatoid arthritis (n = 14) | 3/14 | 3/14 | 7/14 | 1/14 | 1.9 | 0–7.2 | 2.1 | |
| Osteoarthritis (n = 3) | 2/3 | 1/3 | 1.5 | 0.7–3.1 | 1.4 | |||
| Normal synovia (n = 3) | 3/3 | 0 | ||||||
| Neurol. tumour (positive control) | 3/3 | >50 | ||||||