Serum concentrations of soluble adhesion molecules and vascular endothelial growth factor in patients with RA and OA. Data are presented as means (SD), median (25–75 centile). Figures 2–5 show the significances of the differences between patients groups
| OA | RA | Diffuse rheumatoid synovitis | Follicular rheumatoid synovitis | |
|---|---|---|---|---|
| RA, rheumatoid arthritis; OA, osteoarthritis; SD, standard deviation; sICAM-1, soluble intercellular adhesion molecule-1; sVCAM-1, soluble vascular cell adhesion molecule-1; sE-selectin, soluble E-selectin; VEGF, vascular endothelial growth factor. | ||||
| sICAM-1 (ng/ml) | 278.4 (81.7) | 395.6 (125.2) | 351.4 (94.8) | 461.9 (138.4) |
| 273.5 (216.2–313.8) | 372.7 (313.3–453.7) | 342.7 (287.2–408.9) | 435.1 (379.6–533.3) | |
| sVCAM-1 (ng/ml) | 584.7 (154.6) | 832.4 (226.3) | 748.3 (177.6) | 958.4 (237.6) |
| 546.0 (480.0–643.0) | 794.0 (668.5–932.0) | 724.5 (633.5–860.5) | 928.5 (773.0–1135.0) | |
| sE-selectin (ng/ml) | 54.2 (25.4) | 75.6 (33.2) | 70.8 (31.9) | 82.9 (34.8) |
| 51.8 (36.0–66.8) | 73.0 (51.1–95.2) | 68.2 (46.6–90.6) | 80.5 (57.8–100.8) | |
| VEGF (pg/ml) | 229.7 (127.1) | 542.8 (210.6) | 465.9 (178.5) | 658.2 (206.8) |
| 208.8 (134.1–290.8) | 508.5 (392.5–679.0) | 451.7 (356.2–550.0) | 596.5 (528.5–766.9) | |