Extent of skin involvement | Duration of onset— first visit | Duration of d-Pen treatment | Corcicosteroid therapy | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
d-Pen | Diffuse/ limited | I | d-Pen | Duration | I | d-Pen | Duration | I | d-Pen | Corcicosteroid | I | |
d-Pen, d-penicillamine; I, interaction; %VC, percentage vital capacity; %Tlco, percentage carbon monooxidase transfer factor; CT, computed tomograpy. | ||||||||||||
*p<0.05 using Student’s t test. | ||||||||||||
Changes in %VC levels | 0.70 | 0.16 | 0.56 | 0.61 | 0.91 | 0.64 | 0.69 | 0.77 | 0.49 | 0.53 | 0.14 | 0.39 |
Changes in %Tlco levels | 0.77 | 0.06 | 0.30 | 0.83 | 0.55 | 0.95 | 0.69 | 0.70 | 0.22 | 0.77 | 0.40 | 0.63 |
Patients with over 5% reduction of %VC levels | 0.17 | 0.05* | 0.64 | 0.38 | 0.62 | 0.67 | 0.77 | 0.90 | 0.18 | 0.87 | 0.65 | 0.53 |
Patients with over 5% reduction of %Tlco levels | 0.95 | 0.25 | 0.18 | 0.69 | 0.46 | 0.63 | 0.64 | 0.28 | 0.64 | 0.77 | 0.72 | 0.56 |
Patietns with progression of alveolitis or fibrosis in chest CT | 0.43 | 0.63 | 0.21 | 0.28 | 0.83 | 0.61 | 0.94 | 0.42 | 0.07 | 0.82 | 0.25 | 0.94 |
Patietns with progression of alveolitis or fibrosis in chest x ray | 0.69 | 0.69 | 0.22 | 0.56 | 0.79 | 0.49 | 0.70 | 0.20 | 0.17 | 0.74 | 0.46 | 0.27 |