Table 1

Thrombophilic factors in patients with SLE with (Th) or without (Nth) thrombosis

Total (n=48)Th (n=15)NTh (n=33)p Value
LAC, lupus anticoagulant; aCL, anticardiolipin antibodies; anti-β2GPI, anti-β2-glycoprotein I; APCR, activated protein C resistance.
LAC, No (%)15 (31)9 (60)6 (18) 0.006
aCL >20 GPL, No (%)11 (23)6 (40)5 (15)0.074
aCL >30 GPL, No (%)6 (12)5 (33)1 (3) 0.02
Anti-β2GPI+, No (%)9 (19)5 (33)4 (12)0.11
APT+, No (%)17 (35)8 (53)9 (27)0.5
Mean (SD) protein C (activity %)114 (28)102 (24)117 (28)0.45
Mean (SD) free protein S (activity %)85 (23)80 (25)87 (22)0.32
Mean (SD) antithrombin (activity %)102.6 (170)96 (21)105.6 (15)0.28
APCR, No (%)2 (4)1 (7)1 (3)
Prothrombin gene mutation, No (%)1 (2)01 (3)
Mean (SD) homocysteinaemia
    Fasting (μmol/l)11.5 (5)12 (4.2)11.3 (5.6)0.3
    Post-load (μmol/l)46 (34.5)60 (43)41.7 (30.9)0.3