Graded side effects per 100 treatment-years. The grading was done by the treating doctor on the Swedish Medical Products Agency forms
| Etanercept | Infliximab | Leflunomide | ||||
|---|---|---|---|---|---|---|
| Grade | Per 100 years | Number of observations | Per 100 years | Number of observations | Per 100 years | Number of observations |
| Fatal | 1.3 | 3 | ||||
| Life threatening | 2.8 | 3 | ||||
| Serious | 7 | 15 | 10 | 11 | 6 | 4 |
| Moderate | 16 | 36 | 31 | 34 | 28 | 20 |
| Mild | 27 | 61 | 54 | 59 | 22 | 22 |
| Not graded | 2 | 5 | 12 | 9 | ||