Table 1

Specific outcome of 13 pregnancies in seven women with anti-SSA/Ro antibodies who had previously had fetuses with CHB

Patient NoCurrent maternal diagnosisPrevious pregnancies with CHBCorticosteroid treatment of following pregnanciesOutcome of following pregnanciesSexGestational age (WG)Birth weight (g)
*Intrauterine growth restriction (birth weight lower than the third centile for gestational age).
CHB, congenital heart block; WG, weeks’ gestation; SLE, systemic lupus erythematosus; primary SS, primary Sjögren’s syndrome; APL, antiphospholipid antibodies.
1SLE1 CHB (death at 2 days of life)Dexamethasone (4 mg/day)Spontaneous abortion (15 WG)
Prednisone (10 mg/day)Live birthF404130
2SLE1 CHB (death at 6 months of life)Dexamethasone (4.5 mg/day)Spontaneous abortion (18 WG)
Dexamethasone (4.5 mg/day)Stillbirth (24 WG)
Prednisone (10 mg/day)Live birthF382680
3Primary SS2 CHB (pacemaker in both cases)Dexamethasone (4 mg/day)Live birth (adrenal insufficiency)M372140*
Dexamethasone (4 mg/day)Live birth (adrenal insufficiency)M371870*
4Symptom free1 CHB (stillbirth at 30 WG)NoneSpontaneous abortion (11 WG)
NoneLive birthF404030
5Primary SS1 CHB (no need of pacemaker at 4 years)Dexamethasone (5 mg/day)Stillbirth (32 WG) (adrenal hypoplasia)
6Primary SS1 CHB (no need of pacemaker at 10 years)Prednisone (10 mg/day)Live birthF392930
7Primary SS + high APL1 CHB (pacemaker at 18 months)NoneSpontaneous abortion (5 WG)
Prednisone (10 mg/day)Live birthM393080