Table 5

Results of the transmission disequilibrium test performed for HLA-A, B, and C alleles in patients with familial spondyloarthropathy*

All haplotypesHLA-B27 negative haplotypes
HLA alleleTransmittedNot transmittedp/pcorr†TransmittedNot transmittedp/pcorr†
*NA, statistical analysis not applicable because of small sample size; †p values were obtained using binomial probability. pcorr=p value corrected for the number of comparisons; ‡balanced transmission was observed for all the following HLA-A alleles tested: A2, A3, A9 (A23 + A24), A10 (A25 + A26), A11, A19 (A29 + A30 + A31 + A32 + A33 + A34), and A29; §balanced transmission was observed for all the following HLA-B alleles tested: B7, B8, B12 (B44 + B45), B14 (B64 + B65), B15, B16 (B38 + B39), B17 (B57 + B58), B21, and B35; ¶balanced transmission was observed for the following HLA-C alleles tested: C4, C5, C6, C7, and C8.
A1‡20260.381880.05/0.45
A281980.04/0.32661
B5§9180.09
B181560.05/0.6
B601250.09
C1¶27110.01/0.0821NA
C234190.04/0.32390.09
C310250.02/0.168140.21