Table 1

Numbers of pre-RA cases and matched controls reporting heavy cigarette smoking (CS 30+/day) at baseline by relevant categories and odds ratios (ORs) with 95% confidence intervals (95% CIs) for developing ACR+ rheumatoid arthritis

Pre-RA casesRespective matched controls
CategoriesNumberCS 30+/day (%)NumberCS 30+/day (%)OR95% CI
*No association of CS 30+/day with pre-RA RF+ (p=0.99).
†Conversion of RF− at baseline to RF+ after clinical onset of RA.
Pre-RA RF+12 2 (17)* 48 11 (23)* 0.7 0.1 to 3.5
Pre-RA RF−4211 (26)168 8 (5) 7.1 2.6 to 19.1
Entry and post-RA RF−15 4 (27) 60 1 (2)21.52.2 to 210.6
Conversion of pre-RA RF− to RF+†27 7 (26)108 7 (6) 5.11.6 to 16.0