mRNA expression pattern of collagenase 3, MT1-MMP, and gelatinase A in synovial membrane specimens of patients with RA
| mRNA expression | |||
|---|---|---|---|
| Collagenase 3 | MT1-MMP | Gelatinase A | n |
| Synovial membrane specimens of 36 patients with RA and seven control patients without destructive inflammatory joint diseases were investigated by RT-PCR analysis for the expression of collagenase 3, MT1-MMP, and gelatinase A mRNA. | |||
| Patients with RA | |||
| + | + | + | 19 |
| + | − | + | 2 |
| − | + | + | 8 |
| − | − | − | 7 |
| Non-arthritic controls | |||
| − | − | − | 5 |
| − | + | + | 2 |