Age at time of referral (mean) | 51 | 54 | | 55 | |
Sex (male/female) | 3/30 | 4/21 | | 2/40 | |
Xerogenic drugs | 10 (30) | 15 (60) | | 23 (55) | |
Chronic fatigue | 21 (63) | 19 (76) | | 29 (69) | |
Salivary gland swelling* | 17 (51) | 7 (28) | | 8 (19) | |
Connective tissue disease | 0 (0) | RA: | 14 (56) | RA: | 7 (17) |
| | SLE: | 4 (16) | SLE: | 2 (5) |
| | Scleroderma: | 1 (4) | Scleroderma: | 1 (2) |
| | CREST: | 1 (4) | | |
| | Vasculitis: | 1 (4) | | |
| | PBC: | 1 (4) | | |
| | Polymyositis: | 1 (4) | | |
| | Overlap syndrome: | 2 (8) | | |
| | | | | |
Positive salivary gland biopsy | 32 (97) | 24 (96) | | 0 (0) | |
| | | | | |
Positive serology | | | | | |
Anti-SS-A | 28 (85) | 13 (52) | | 3 (7) | |
Anti-SS-B | 15 (45) | 8 (32) | | 1 (2) | |
Positive eye test(s)† | 25 (76) | 17 (68) | | 18 (43) | |
Parotid sialography‡ | | | | | |
Sialectasia (positive for SS) | 28 (100) | 16 (76) | | 3 (8) | |
Subjective complaints§ | | | | | |
Dry eyes | 24 (73) | 20 (80) | | 28 (67) | |
Dry mouth | 32 (96) | 23 (92) | | 31 (74) | |