Table 2

Risk factors at disease onset for a higher mortality in patients with SLE

AllNot alive
No%%tpRR (95% CI)
Multivariable Cox regression; age and sex adjusted. *Results for Ro, nRNP antibodies are calculated with χ2 tests, as a Cox regresion is not possible with zero values; NC, not calculated.
t=years after diagnosis, when 25% of the patients have died.
Heart disease includes carditis, coronary heart disease, myocardial infarction and congestive heart failure. CNS disease includes psychosis, seizure, stroke, haemorrhage, CNS vasculitis. Reduced creatintine clearance: <70 ml/min.
All patients with SLE3381001017.8
Risk factors:
    Heart disease25 72810.40.051.5 (1.0 to 2.4)
    CNS disease33101810.40.061.6 (0.98 to 2.5)
    Nephritis (ACR)77232010.4<0.051.6 (1.1 to 2.4)
    Reduced creatinine clearance391233 9.7<0.011.8 (1.2 to 2.7)
Protective factors:
    Ro antibodies*3811 0NC.*<0.05*0.1*
    nRNP antibodies*32 9 0NC*<0.05*0.1*