Table 3

Spearman correlation coefficients between measures of disease activity (ESR and DAS) and changes in purine enzyme activities during 48 weeks of methotrexate treatment in patients with rheumatoid arthritis

ESR t=0 (n=103)Change in ESR after 48 weeks (n=76)DAS t=0 (n=103)Change in DAS after 48 weeks (n=76)
*ESR, erythrocyte sedimentation rate; DAS, disease activity score.
5`NT0.16 p=0.110.25 p=0.030.23 p=0.010.11 p=0.34
ADA−0.06 p=0.55−0.10 p=0.390.04 p=0.680.10 p=0.38
PNP−0.09 p=0.37−0.16 p=0.19−0.07 p=0.47−0.09 p=0.47
HGPRT−0.06 p=0.53−0.04 p=0.710.13 p=0.180.07 p=0.54