Table 1

Patient characteristics and treatment summary

Case No and diagnosisRituximab dosesMarker pretreatmentMarker post-treatment
Anti-GM, antiglomerular basement membrane antibodies.
1. Mixed essential cryoglobulinaemia type II6Cryocrit: 1.7%Cryoglobulins: negative
(fractionation: IgG 0.21 g/l, IgM 0.320 g/l)Lymphocyte Ct: 1938 ×106/l
Lymphocyte Ct: 2218 ×106/l
2. Goodpasture's syndrome6Anti-GM: 51 U/mlAnti-GM: none
Lymphocyte Ct: 495 ×106/lLymphocyte Ct: 836 ×106/l
3. Immune complex vasculitis8C1q: 69 μg (normal <4 μg)C1q: <4 μg
Raji cell: 275 μg Eq/ml (normal <12 μg Eq/ml)Raji cell: 7.3 μg Eq/ml
Lymphocyte Ct: 816 ×106/lLymphocyte Ct: 1491 ×106/l