Table 1

Demographic and clinical data of the eight patients with rheumatoid arthritis from Leiden and the nine patients from Daw Park, who were studied for variations in cell infiltrate, and expression of matrix metalloproteinases and granzyme B of synovial tissue from cartilage-pannus junction and suprapatellar pouch

Patient Age (years) Sex (M/F) Disease duration (months) DMARDs1-150 CRP1-150(mg/l) RF1-150(+/−) Erosions (+/−)
154M30Plaquenil14+
255M27637
348F84MTX1-150 4+
465M288MTX27++
558F276MTX17+
680F336Prednisone45++
780F336Prednisone45++
843F120MTX, prednisone, cyclosporin29++
977M17Gold1
1076F120Cyclosporin46++
1172F1335++
1260F24Plaquenil80
1377M180Gold16++
1470M1Gold, MTX116+
1575F3Gold47+
1676F1Gold32
1759F216MTX108++
  • 1-150 DMARDs = disease modifying antirheumatic drugs; CRP = C reactive protein; RF = rheumatoid factor, MTX = methotrexate.