CD3+ | CD3+/CD56+ | p Value | |
HC (n=15) | |||
IFNγ | 33.0 (13.1–53.9) | 19.1 (8.2–48.4) | 0.019 |
IL2 | 25.7 (13.4–39.6) | 19.2 (1.0–36.0) | 0.049 |
IL4 | 1.8 (0.4–3.6) | 13.2 (1.3–35.8) | 0.000 |
IL10 | 1.1 (0.2–5.6) | 33.5 (11.3–55.9) | 0.000 |
SpA (n=20) | |||
IFNγ | 20.9 (9.5–65.1) | 16.2 (3.9–70.8) | NS |
IL2 | 17.5 (7.5–35.4) | 12.5 (2.2–51.8) | 0.011 |
IL4 | 1.5 (0.3–8.7) | 11.1 (0.2–68.0) | 0.000 |
IL10 | 3.8 (0.9–15.4) | 42.8 (6.5–82.4) | 0.000 |
RA (n=19) | |||
IFNγ | 19.9 (8.4–53.4) | 11.8 (4.5–48.1) | 0.019 |
IL2 | 31.2 (13.1–56.7) | 11.4 (2.5–33.1) | 0.000 |
IL4 | 1.0 (0.3–2.7) | 3.0 (0.2–14.4) | 0.005 |
IL10 | 5.4 (1.8–37.5) | 38.1 (10.3–68.0) | 0.000 |
NS = not significant.
Percentage of positive cells for interferon (IFN)γ, interleukin (IL)2, IL4, and IL10 was assessed by flow cytometry. Results are expressed as median (range) % of CD3+ cells and CD3+/CD56+ cells expressing IFNγ, IL2, IL4, and IL10