Table 2

Results of minor salivary gland biopsies, and of Schirmer's and salivary secretion tests

RA (n=25)
N (%)
MCTD (n=19) N (%) AS (n=19)
N (%)
SpA (n=22)
N (%)
p Value between groups2-150 Post hoc testing
Focal sialadenitis20  (80)17  (94)2-152 11  (58)9  (41)0.001RA>SpA, MCTD>AS, MCTD>SpA
Decreased salivary secretion2-151 3 (12)11 (61)4 (22)0 (0)<0.001RA<MCTD, MCTD>SpA
Oral symptoms11 (44)14 (74)8 (42)3 (14)0.002MCTD>SpA
Decreased tear secretion2-153 11 (44)13 (87)6 (32)3 (15)0.021MCTD>SpA
Ocular symptoms13 (52)12 (63)10 (53)10 (45)0.73
Patients with Sjögren's syndrome2-154 7 (28)11 (73)5 (26)3 (15)0.021RA<MCTD, MCTD>AS, MCTD>SpA
  • 2-150 χ2 test.

  • 2-151 Either unstimulated or stimulated salivary excretion abnormal. Not studied in four patients with MCTD, two with SpA, and one with AS.

  • 2-152 One minor salivary gland biopsy sample was not representative and was therefore excluded.

  • 2-153 Not studied in four patients with MCTD and two with SpA.

  • 2-154 Fullfilling the European criteria for secondary Sjögren's syndrome.5

  • RA = Rheumatoid arthritis; MCTD = mixed connective tissue disease; AS = ankylosing spondylitis; SpA = spondyloarthropathy.