Table 3

Clinical chart items that correlated with disease activity (consensus score) on univariate analysis

	Whole series p	dSSc p	lSSc p
Generalised complaints	0.0019	0.0100
Δ-Gen	0.0030	0.0013
Scleredema	0.0041		0.0015
Melanoderma	0.0002		0.0018
TSS^*>20	0.0001		0.0035
Δ-Skin	0.0001	0.0001	0.0001
Digital necrosis	0.0001		0.0001
Δ-Vasc	0.0001	0.0001	0.0001
Dyspnoea	0.0001	0.0084	0.0046
↓ FVC^*	0.0001	0.0251	0.0032
↓ Tlco ^*	0.0001	0.0087	0.0020
Δ-HL^*	0.0001	0.0001	0.0001
Arthritis	0.0001	0.0432	0.0154
Muscle involvement	0.0007	0.0316	0.0227
Δ-JM^*	0.0001	0.0001	0.0001
Tendon rubs	0.0089
ESR^* >30 mm/1st h	0.0001	0.0209	0.0001
↑ CRP^*	0.0070
↑ LDH^*	0.0033	0.0414	0.0472
↑ CK^*	0.0420	0.0270
Hypocomplementaemia^3-151	0.0124		0.0487

TSS = total skin score; FVC = forced vital capacity <80% of predicted value; Tlco = carbon monoxide transfer factor <80% of the predicted value; Δ-HL = cardiopulmonary; Δ-JM = articular/muscular; ESR = erythrocyte sedimentation rate; CRP = C reactive protein; CK = creatine kinase; LDH = lactic dehydrogenase.
↵3-151 Reduced C3 or C4 complement levels.