Table 4

Data distribution depending on AKA, IgA RF, and ANCA positivity in 96 patients with RA (mean (SD) values shown where appropriate)

Clinical and paraclinical variables AKA positive (n=42) AKA negative (n=54) p value IgA RF positive (n=74) IgA RF negative (n=22) p value ANCA positive (n=32) ANCA negative (n=64) p value
Age (years)56 (9.2)55 (12.5)NS57 (9.5)50 (14.3)0.034-160 57 (13)54 (10)NS
Male/female (n)7/356/48NS10/643/19NS4/289/55NS
Duration of disease (years)6.9 (6.2)8.7 (7.9)NS8 (7.5)7.4 (6.5)NS10 (7.8)6.7 (6.7)0.034-160
Morning stiffness (hours)2.2 (0.8)1.9 (0.9)NS2 (0.9)1.7 (0.9)NS2 (0.9)1.9 (0.9)NS
Hand deformity (n)2021NS338NS1823NS
Constitutional symptoms (n)30260.024-150 5060.00084-150 1937NS
Extra-articular symptoms (n)184-151 94-152 0.0054-150 243NS174-154 104-163 0.00014-150
Functional class ⩾II (n)4133<0.00014-150 63110.00064-150 30440.0064-150
Steinbrocker's score ⩾2 (n)27220.024-150 3910NS22270.014-150
Ritchie index >15 (n)4234<0.00014-150 63130.0084-150 29470.054-150
DAS (range)6.5 (0.9) (4.2–8.4)4.2 (0.7) (2.9–6.8)<0.00014-160 5.4 (1.4) (3.1–8.4)4.6 (1.2) (2.9–7.8)0.014-160 5.7 (1.3) (3.7–7.9)5 (1.4) (2.9–8.4)0.024-160
ESR (mm/1st h)33.2 (15)32.7 (14.9)NS34.2 (15.3)29.2 (12.6)NS35 (1631.8 (14.3)NS
Haemoglobin (g/l)116 (14.8)115 (14.5)NS115.5 (14.6)116.2 (14.7)NS114.5 (12.8)117.8 (45.6)0.034-160
IgA RF positive (n)37370.024-150 2549NS
IgA RF levels (AU/ml)73.4 (32.6)53.4 (38.8)0.0074-160 68.6 (37.2)58.9 (37.4)NS
IgM RF positive (n)3639NS696<0.00014-150 2649NS
IgM RF levels (IU/ml)165.8 (36.4)128.4 (31.6)NS181 (131)22 (39.2)<0.00014-160 191.4 (149.5)121.4 (120.7)0.0254-160
IgA, IgM RF positive (n)3435NS2445NS
ANCA positive (n)1814NS257NS
ANA positive (n)2227NS3811NS2029NS
  • 4-150 χ2 test.

  • 4-160 Student's t test.

  • 4-151 Including rheumatoid vasculitis (7), rheumatoid nodules (5), pleuritis (5), Sjögren's syndrome (1), Felty's syndrome (1), conjunctivitis (1).

  • 4-152 Including rheumatoid nodules (4), rheumatoid vasculitis (3), conjunctivitis (2), Raynaud's syndrome (1), pleuritis (1).

  • 4-154 Including rheumatoid vasculitis (8), pleuritis (5), rheumatoid nodules (3), conjunctivitis (2), Felty's syndrome (1), Raynaud's syndrome (1).

  • 4-163 Including rheumatoid nodules (6), vasculitis (2), conjunctivitis (1), pleuritis (1), Sjögren's syndrome (1).

  • Some patients had more than one extra-articular symptom.

  • For definitions of abbreviations, see text.