Table 1

Baseline data. Values are medians (ranges in parentheses). NS indicates no significant difference

All knees RA knees Non-RA knees Mann-Whitney
(RA v non-RA)
Number of knees (patients)15 (12)9 (7)6 (5)
Age (years)58 (20–70)64 (20–70)25 (20–60)p<0.01
Duration of knee symptoms (years)2 (0.2–13)2 (0.2–13)2.5 (0.2–10)p<0.05
Knee pain (VAS1-150)6.3 (2.8–10)7.2 (5.7–10)3.7 (2.8–8.8)NS
Number of swollen and/or tender joints5 (1–26)7 (5–26)1.5 (1–5)p<0.01
Serum CRP1-150 (nmol/l)170 (30–1590)324 (50–1413)119 (30–1590)NS
ESR1-150 (mm/1st h)42 (8–95)45 (10–95)41 (8–70)NS
Macroscopic synovitis (average grade)3.3 (1.0–4.0)3.3 (1.0–3.8)3.1 (2.3–4.0)NS
Histological synovitis (average grade)1.8 (0.3–2.7)1.8 (1.2–2.7)1.9 (0.3–2.0)NS
Synovial membrane volume (cm3)62 (21–177)59 (46–128)66 (21–177)NS
Joint fluid volume (cm3)45 (6–173)36 (15–94)70 (6–173)NS
Bone erosion score0 (0–5)1 (0–5)0 (0–1)p<0.05
Progression in bone erosion score0 (0–4)0 (0–4)0 (0)NS
Duration of clinical remission (days)360 (60–360)330 (60–360)360 (60–360)NS
  • 1-150 VAS = visual analogue scale; CRP = C reactive protein; ESR = erythrocyte sedimentation rate.