Table 2

Definition of defined antinuclear antibody specificities

Anti-SSAPositive on immunodiffusion or reactive with at least 1 of the SSA/Ro particles (Ro52 and Ro60) on LIA2-150
Anti-SSBPositive on immunodiffusion or reactive with SSB on LIA
Anti-RNPPositive on immunodiffusion or reactive with at least 2 of the RNP particles (RNP-A, RNP-C, and RNP-70K) on LIA
Anti-SmPositive on immunodiffusion or reactive with Sm-D on LIA
Anti-Scl70Positive on immunodiffusion or on LIA
Anti-Jo-1Positive on immunodiffusion or on LIA
AnticentromereCharacteristic fluorescence pattern on HEp-2 cells or reactive with Cenp-B on LIA
Anti-rRNPReactive with synthetic peptide representing the 22 C-terminal epitope shared by the phosphoproteins P0, P1, and P2, on LIA
Anti-dsDNACharacteristic fluorescence pattern onCrithidia luciliae
  • 2-150 LIA = line immunoassay.