Tables 1A and B Brain metabolite concentrations (mmol/l) and concentration ratios in patients with systemic lupus erythematosus (SLE) and normal subjects.

tCr tCho NAA mI
Patients with SLE1-152 (n=9)6.26 (0.60)2.001-150 (0.23)9.691-150(1.52)6.821-160 (1.40)
SLE major (n=5)6.21 (0.74)1.91 (0.11)8.801-165 (1.31)6.871-160 (0.85)
SLE minor (n=4)6.33 (0.64)2.111-150 (0.31)10.78 (0.93)6.75 (1.98)
Lesions1-154(n=4)4.86 (1.64)1.51 (0.40)5.331-165 (3.74)5.73 (2.53)
Normal subjects‡‡(n=8)6.20 (0.28)1.78 (0.15)11.0 (0.60)5.19 (0.66)
Table 1B
NAA/tCr mI/tCr NAA/tCho NAA/mI
Patients with SLE1-152 (n=9)1.56 (0.30)1.071-150(0.17)4.871-165 (0.77)1.531-150 (0.58)
Normal subjects‡‡(n=8)1.78 (0.15)0.84 (0.10)6.22 (0.64)2.16 (0.33)
  • One way analysis of variance of patient groups compared with normal subjects:

  • 1-150 p<0.05;

  • 1-160 p<0.01;

  • 1-165 p<0.005.

  • One way analysis of variance of SLE major compared with SLE minor:p<0.05.

  • 1-152 Average of all patient data using individual means of data for patients with multiple visits.

  • Data from normal appearing parietal white matter (NAPWM) in patients with SLE.

  • 1-154 Data from large lesions in patients with SLE major.

  • 1-164 Average from NAPWM of eight normal volunteers.