Table 2

Infiltration by CD3+ T cells, CD4+ cells, CD8+ cells, CD68+ macrophages, and expression of the adhesion molecules ICAM-1 and VCAM-1 and the activation antigen HLA-DR in muscle biopsy specimens from patients with osteoarthritis (OA), rheumatoid arthritis (RA) without any signs of vasculitis (RA−), patients with RA with clinical signs of vasculitis without proof on routine histology (RA+), and patients with RA with histologically proved vasculitis (RV).Values are the mean semiquantitative scores (standard error)

CD3 CD4 CD8 CD68 ICAM-1 VCAM-1 HLA
OA (n=5)0.6 (0.2)0.6 (0.2)0.4 (0.2)1 (0)1 (0)0.6 (0.2)1 (0.6)
RA− (n=6)0.5 (0.2)0.7 (0.2)0.2 (0.2)1.2 (0.3)1.2 (0.2)0.2 (0.2)1 (0.3)
RA+ (n=11)1.72-150 (0.2)1.52-150 (0.2)1.32-150 (0.3)2.32-150(0.2)22-150 (0.3)1.42-150 (0.3)2.62-150 (0.3)
RV (n=14)22-151(0.3)2.12-151 (0.3)1.82-151 (0.3)2.62-151 (0.2)2.72-151(0.3)1.92-151 (0.3)2.82-151 (0.2)

  • ↵2-150 p<0.05 (Student's t test for differences between RA− and RA+).

  • ↵2-151 p<0.05 (Student's t test for differences between RA− and RV).

  • The difference between RA+ and RV was not statistically significant.