Table 3

Secondary outcome measures: improvements and differences between intervention groups^3-150

		Exercise therapy				Control		Difference (95% CI) exercise therapy − controls	Effect size
		n	Mean change^3-151			n	Mean change^3-151	Difference (95% CI) exercise therapy − controls	Effect size
Drug use: paracetamol
Week 12	93	35%		98	51%	−16% (−29% to −3%)	0.33
Week 24	90	39%		94	55%	−17% (−30% to −3%)	0.32
Week 36	90	41%		93	57%	−17% (−30% to −3%)	0.32
Global perceived effect: improved^3-152
Week 12	91	47%		98	18%	28% (15% to 42%)	0.64
Week 24	88	49%		91	25%	24% (10% to 38%)	0.50
Week 36	90	46%		93	29%	17% (3% to 31%)	0.35
Self reported disability^3-153
Week 12	93	−1.1		98	−0.0	−1.1 (−2.3 to 0.1)	0.26
Week 36	90	−1,2		92	−0,3	−0.8 (−2.2 to 0.5)	0.18
Muscle strength hip
Week 12	91	0.22		94	0.04	0.17 (0.02 to 0.33)	0.32
Week 24	85	0.16		87	0.13	0.04 (−0.14 to 0.21)	0.06
Week 36	85	0.26		87	0.22	0.04 (−0.12 to 0.21)	0.08
Muscle strength knee
Week 12	92	0.19		98	0.06	0.13 (−0.04 to 0.29)	0.22
Week 24	88	0.14		91	0.14	0.00 (−0.17 to 0.17)	0.00
Week 36	86	0.19		90	0.19	0.00 (−0.18 to 0.17)	0.01
Joint range of motion hip
Week 12	92	0.21		98	0.06	0.15 (−0.03 to 0.32)	0.23
Week 24	87	0.36		90	0.27	0.09 (−0.13 to 0.31)	0.11
Week 36	87	0.19		89	0.19	0.00 (−0.21 to 0.22)	0.01
Joint range of motion knee
Week 12	92	0.17		98	0.09	0.08 (−0.09 to 0.25)	0.13
Week 24	90	0.11		94	0.15	−0.04 (−0.24 to 0.17)	0.05
Week 36	87	0.11		90	0.05	0.05 (−0.15 to 0.25)	0.10
Physical activity: improved^3-153 ^3-154
Week 12	87	46%		97	48%	−2% (−17% to 13%)	0.04
Week 36	89	42%		91	49%	−8% (−22% to 7%)	0.15

↵3-150 Analyses are adjusted for baseline differences (fear avoidance beliefs towards physical activity, use of paracetamol, use of NSAIDs) and baseline score on specific outcome parameter.
↵3-151 For drug use follow up scores are presented; percentage of patients taking drugs.
↵3-152 Results on an eight point scale are dichotomised as improved (completely recovered, very much improved, and much improved) and not improved (slightly improved, not changed, slightly worsened, much worsened, and vastly worsened).
↵3-153 Not assessed at 24 week follow up.
↵3-154 Results are dichotomised as improved (increase in physical activity level, change = 1 min/week) versus not improved (stabilisation or decrease in physical activity, change = 0 min/week).