Composition of stimulated glandular saliva from SS positive patients (groups A and B: primary and secondary Sjögren's syndrome respectively), SS negative patients (group C), and healthy controls (group D)
| Parotid glands (mean of two sides) | Submandibular/sublingual glands | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Group A (n=33) | Group B (n=25) | Group C (n=42) | Group D (n=36) | Group A (n=33) | Group B (n=25) | Group C (n=42) | Group D (n=36) | ||
| Sodium (mmol/l) | 26 (23)3-150 3-151 | 23 (22)3-150 | 4 (4)3-151 | 14 (12) | 20 (15)3-150 3-151 | 16 (11)3-150 3-151 | 6 (6)3-151 | 11 (6) | |
| Potassium (mmol/l) | 23 (6) | 23 (9) | 30 (21)3-151 | 24 (6) | 21 (21) | 18 (7) | 20 (6)3-151 | 17 (6) | |
| Chloride (mmol/l) | 30 (14)3-151 | 37 (28)3-150 3-151 | 18 (6) | 16 (12) | 27 (15)3-151 | 34 (35)3-150 3-151 | 16 (5) | 16 (6) | |
| Calcium (mmol/l) | 1.3 (1.0) | 1.0 (0.2) | 1.3 (0.8) | 0.8 (0.6) | 1.9 (0.9) | 1.9 (0.5) | 2.2 (1.6) | 1.7 (0.6) | |
| Phosphate (mmol/l) | 4.5 (2.4) | 4.2 (1.6) | 5.8 (2.9) | ND | 2.3 (1.2)3-150 | 2.5 (1.2)3-150 | 3.9 (1.7) | ND | |
| Urea (mmol/l) | 5.6 (2.0) | 4.9 (2.4) | 6.1 (2.5) | 3.8 (1.2) | 2.9 (1.8) | 3.8 (2.3) | 4.0 (1.9) | 2.5 (0.6) | |
| Total protein (g/l) | 1.2 (0.5)3-151 | 1.6 (1.3)3-151 | 1.2 (0.6)3-151 | 0.6 (0.6) | 0.6 (0.3) | 0.8 (0.5) | 0.7 (0.4) | 0.8 (0.6) | |
| Total protein (g/min) | 0.1 (0.1) | 0.3 (0.5) | 0.2 (0.2) | 0.3 (0.3) | 0.2 (0.2) | 0.3 (0.6) | 0.3 (0.3) | 0.4 (0.3) | |
| Amylase (103U/l) | 519 (344) | 618 (474) | 842 (486)3-151 | 590 (510) | 117 (97) | 162 (293) | 138 (121) | ND | |
| Amylase (103U/min) | 59 (65) | 180 (295) | 152 (142) | 307 (264) | 45 (60) | 27 (60) | 58 (70) | ND | |
Data are expressed as mean (SD) and are based on the number of patients with available information.
↵3-150 Significant difference between SS positive and SS negative patients.
↵3-151 Significant difference between patients and healthy controls. Statistical test used: analysis of variance (multi comparison according to Scheffé).
ND, Not determined.