Pain ratings (VAS, 0 = no pain, 10 = extremely painful) in patients with leech treatment and in controls; mean score and 95% confidence interval ( x± 1.96 SEM)
| Baseline | Day 3 | Day 4 | Day 6 | Day 10 | Day 28 | |
| Leeches (n=10) | 7.4 (6.3 to 8.5) | 7.2 (6.2 to 8.2) | 4.1 (2.8 to 5.4) | 2.4 (1.2 to 3.6)1-150 | 1.3 (0.5 to 2.8)1-150 | 1.0 (0.5 to 1.5)1-150 |
| Controls (n=6) | 6.3 (4.8 to 7.8) | 5.8 (4.3 to 7.4) | 5.8 (4.4 to 7.3) | 5.2 (3.6 to 6.7) | 5.2 (3.8 to 6.5) | 4.8 (3.8 to 5.9) |
Days 1–3: Pretreatment observation period. First rating after leeches treatment on day 4. Further ratings at days 6, 10, and 28.
↵1-150 p<0.05 between group differences.