The Chapel Hill nomenclature
| Large vessel vasculitis | |
|---|---|
| Giant cell (temporal) arteritis | Granulomatous arteritis of the aorta and its major branches, with a predilection for the extracranial branches of the carotid artery. Often involves the temporal artery. Usually occurs in patients older than 50 and often is associated with polymyalgia rheumatica. |
| Takayasu arteritis | Granulomatous inflammation of the aorta and its major branches. Usually occurs in patients younger than 50. |
| Medium sized vessel vasculitis | |
| Polyarteritis nodosa | Necrotising inflammation of medium sized or small arteries without glomerulonephritis or vasculitis in arterioles, capillaries, or venules. |
| Kawasaki disease | Arteritis involving large, medium sized, and small arteries, and associated with mucocutaneous lymph node syndrome. Coronary arteries are often involved. Aorta and veins may be involved. Usually occurs in children. |
| Small vessel vasculitis | |
| Wegener's granulomatosis | Granulomatous inflammation involving the respiratory tract, and necrotising vasculitis affecting small to medium sized vessels (that is, capillaries, venules, arterioles, and arteries). Necrotising glomerulonephritis is common. |
| Churg-Strauss syndrome | Eosinophil rich and granulomatous inflammation involving the respiratory tract, and necrotising vasculitis affecting small to medium sized vessels, and associated with asthma and eosinophilia. |
| Microscopic polyangiitis | Necrotising vasculitis, with few or no immune deposits, affecting small vessels (that is, capillaries, venules, or arterioles). Necrotising arteritis involving small and medium sized arteries may be present. Necrotising glomerulonephritis is very common. Pulmonary capillaritis often occurs. |
| Henoch-Schönlein purpura | Vasculitis, with IgA dominant immune deposits, affecting small vessels (that is, capillaries, venules, or arterioles). Typically involves skin, gut, and glomeruli, and is associated with arthralgias or arthritis. |
| Essential cryoglobulinaemic vasculitis | Vasculitis, with cryoglobulin immune deposits, affecting small vessels (that is, capillaries, venules, or arterioles), and associated with cryoglobulins in serum. Skin and glomeruli are often involved. |
| Cutaneous leucocytoclastic angiitis | Isolated cutaneous leucocytoclastic angiitis without systemic vasculitis or glomerulonephritis. |
Modified from reference 3.