Table 1

Major associated conditions, significant laboratory data, and treatment in patients with gout receiving allopurinol

Group A n=52 Group B n=68 p Value
Diabetes mellitus (n, %)3 (5.7)7 (10.2)NS
Hypertension (n, %)13 (25)20 (29)NS
Hyperlipidaemia (n, %)13 (25)12 (18)NS
Haemoglobin (g/l)1-150 160 (13)146 (26)0.002
Packed cell volume0.49  (0.04)0.46  (0.08)0.005
Creatinine (μmol/l)1-150 100 (18)120 (53)0.003
BUN (mmol/l)1-150 11.5 (4.5)16.5 (8.0)0.000
CrC (ml/min)1-150 103.8 (21.8) [99.7]54.6 (20.1) [52.9]0.000
Allopurinol maintenance doses (mg/day)
 100–<300, n (%)4 (8)1 (2)NS
 300, n (%)46 (88)62 (91)NS
 >300, n (%)2 (4)5 (7)NS
Other treatments, n (%)34 (65)49 (72)NS
  • BUN = blood urea nitrogen; CrC = creatinine clearance.

  • 1-150 Values represent mean (SD) [median].