Table 5

English literature search 1960–98: case reports of avascular necrosis (AVN) in primary or secondary antiphospholipid syndrome (APS)

Authors (reference) 1/ or 2/ APS Age Sex Race Site(s) of osteonecrosis Previous corticosteroid use Remarks
Alijotaset al 29 1/32FWLunate−ve
Velaet al 31 1/32FWLeft femoral head−ve
Seleznick et al 32 1/47FACLeft femoral head, right knee−ve
Egan et al 12 1/, catastrophic25FWProximal femur, T8, L4, L5   vertebrae, manubrium, lower sternum, (shoulders, elbows, wrists, ankles, tibiae)−ve1 month after hysterectomy for   carcinoma of uterus, concomitant AIHA, leg ulcer, and RTA (IV)
  • 1/ = primary; 2/ = secondary; AC = Afro-Caribbean; AIHA = autoimmune haemolytic anaemia; DVT = deep vein thrombosis; F = female; RTA = renal tubular acidosis; W = white.