Baseline | Day 14 | Day 42 | Day 84 | |
Night pain (0–3) | 3 (1–3) | 1 (0–2)3-150 | 0 (0–2)3-150 | 1 (0–1)3-150 |
Morning stiffness (min) | 90 (30–240) | 15 (0–120)3-150 | 10 (0–120)3-150 | 5 (0–120)3-150 |
Pain spine (0–100) | 57 (4–95) | 20 (3–68)3-151 | 15 (0–80)3-151 | 11 (1–60)3-150 |
BASDAI3-152 (0–100) | 62.4 (28.8–82.4) | 18.3 (5.0–60.6)3-150 | 9.5 (3.2–59.5)3-150 | 11.3 (1.2–44.0)3-150 |
BASFI3-152 (0–100) | 77.4 (9.9–94.2) | 29.4 (1.8–71.6)3-150 | 13.1 (4.1–66.5)3-150 | 22.3 (1.0–63.2)3-150 |
Dougados FI3-152 (0–40) | 21 (7–31.5) | 12 (3–24)3-150 | 7.5 (2.0–22.0)3-150 | 8.5 (0.5–21.0)3-150 |
Spinal pain (0–3) | 2 (0–3) | 1 (0–3)NS | 0 (0–3)3-151 | 0 (0–2)3-151 |
BASMI3-152(0–10) | 5 (3–9) | 5 (0–9)3-151 | 5 (1–9)3-151 | 5 (1–9)3-151 |
Occiput to wall (cm) | 12 (3.7–21.5) | 9.5 (0–21.0)3-151 | 9 (2.5–21.0)3-150 | 7.7 (2.5–22.0)3-150 |
Chest expansion (cm) | 1.8 (1.5–3.2) | 3.5 (1.0–5.5)3-151 | 3 (1.8–5.0)3-150 | 3.8 (1.7–5.5)3-150 |
Fingers to floor (cm) | 24 (5.5–38.0) | 18 (0–34.0)3-150 | 17.5 (0–35.4)3-150 | 15 (0–20.3)3-150 |
Dougados articular index (0–30) | 6 (1–15) | 2 (0–7)3-150 | 2 (0–3)3-150 | 0 (0–4)3-150 |
Values are given as median (range)
↵3-151 p⩽0.05;
↵3-150 p⩽0.01; NS = not significant (determined by Wilcoxon signed ranks test compared with baseline).
↵3-152 BASDAI = Bath Ankylosing Spondylitis Disease Activity Index; BASFI = Bath Ankylosing Spondylitis Functional Index; Dougados FI = Dougados Functional Index; BASMI = Bath Ankylosing Spondylitis Metrology Index.