Table 2

Global and peripheral assessments before and at days 3, 7, and 14 after treatment

Baseline Day 3 Day 7 Day 14
Global assessments (n=21)
Patient global (0–100)57 (27–100)33 (2–81)2-160 24 (2–69)2-160 23 (3–52)2-160
Patient pain (0–100)70 (23–100)29 (4–90)2-160 23 (2–91)2-160 25 (4–61)2-160
Doctor global (0–100)57 (12–79)33 (7–59)2-160 24 (7–37)2-160 23 (5–36)2-160
ESR2-151 (mm/1st h)44 (10–101)33 (7–87)2-160 13 (4–64)2-160 6 (2–30)2-160
CRP2-151 (g/l)0.046 (0.007–0.29)0.018 (0.003–0.152)2-160 0.004 (0–0.015)2-160 0.003 (0–0.01)2-160
Peripheral assessments (n=18)
Morning stiffness (min)90 (10–300)5 (0–150)2-160
Pain peripheral joints (0–100)75 (20–99)27 (1–49)2-160
Tender joint count (0–68)6 (1–18)3 (0–17)2-160 1 (0–15)2-160 2 (0–11)2-160
Swollen joint count (0–66)3.5 (1–12)1.5 (0–10)2-150 2 (0–5)2-160 1 (0–9)2-160
  • Values are given as median (range).

  • 2-150 p⩽0.01;

  • 2-160 p⩽0.001 (determined by Wilcoxon signed ranks test compared with baseline).

  • 2-151 ESR = erythrocyte sedimentation rate; CRP = C reactive protein.