Table 4

Inhibition of binding to solid phase histone by free histone: differences between antibodies and the immunoglobulins from rheumatoid arthritis patient serum samples

Specimen% Inhibition with free histone as detected by enzyme conjugates specific for
FcγFcIgA α chain
HS-14-150 96NANA
HS-24-150 89NANA
Heated NS16NA18
R11NA16NA
R1219NA0c
R13NA23NA
R141822NA
R15NA4NA
R1625210c
R1715NA0c
R188NANA
R191131NA
R20460c 0c
R210NANA
R22NA100c
R2325NA0c
R2436NA0c
R25NA310c
R26204020
R2715NANA
Average for RA20202
  • 4-150 HS-1 and HS-2 are histone-specific patient serum samples.

  • 0c slight enhancement was taken as 0.

  • NA = not applicable (when A450 was within normal range).