Rheumatoid synovial cells at early passage were stimulated with interferon γ (IFNγ), tumour necrosis factor α (TNFα), interleukin 1β (IL1β), interleukin 2 (IL2), or interleukin 6 (IL6) for 24 hours. They were assayed for c-fos expression in a transient assay using pBL-fos-CAT
| Cytokine | 10 U/ml | 50 U/ml | 100 U/ml |
| Exp. 1 | |||
| IFNγ | 1.11-150 | 1.0 | 1.3 |
| TNFα | 1.2 | 1.0 | 5.6 |
| IL1β | 1.2 | 1.3 | 1.2 |
| IL2 | 1.1. | 1.1 | 1.1 |
| IL6 | 1.2 | 1.6 | 2.2 |
| Medium | 0.9 | ||
| Exp. 2 | |||
| IFNγ | 1.0 | 2.0 | 0 |
| TNFα | 1.2 | 10.0 | 8.2 |
| IL1β | 2.2 | 1.6 | 1.8 |
| IL2 | 1.6 | 0.2 | 2.0 |
| IL6 | 1.2 | 3.0 | 6.2 |
| Medium | 1.2 | ||
↵1-150 pg/ml.