Table 4

Comparison of IL1β and IL17 effects on proteoglycan synthesis rate ex vivo and in vivo

Ex vivo In vivo
Control1228 (510)11 753 (2716)
IL1β (10 ng/knee)651 (328)4-150 8 070 (1729)4-150
IL17 (10 ng/knee)1194 (217)4-151 10 795 (1117)4-151
IL17 (1 ng/knee)1327 (296)4-151 10 649 (3130)4-151
  • Counts (cpm/patella) are given as means (SD).

  • 4-150 p<0.01 versus control;

  • 4-151 p NS versus control using an unpairedt test.