Table 4

Discriminative ability of the preliminary ACR improvement criteria at different thresholds, EULAR response criterion, ACR and DAS remission criteria to distinguish between two treatment groups at two points of follow up

CriterionWeek 16Week 28
Improved4-150χ2p ValueImproved4-150χ2p Value
ACR improvement
 0% Threshold88v 63%12.90.000382v 62%7.30.007
 10% Threshold78 v44%18.0<0.000174 v49%9.70.002
20%Threshold 72 v32% 25.7 <0.0001 72 v49% 8.6 0.003
 30% Threshold64 v24%25.7<0.000167 v39%12.10.0005
 40% Threshold58v 16%28.6<0.000155v 30%9.80.002
50%Threshold 43 v14% 16.6 <0.0001 49 v27% 8.1 0.004
 60% Threshold26 v8%9.70.00237 v22%4.40.04
70%Threshold 16 v6% 3.6 0.06 29 v10% 8.8 0.003
EULAR response20.2<0.000113.40.001
 Good + moderate86 v56%86 v63%
 Good37 v15%47 v24%
ACR remission
  ‘Probable’12v 6%1.40.2321v 11%2.70.10
DAS remission
  (DAS ⩽1.6)12 v9%0.40.5417 v10%1.60.20
  • 4-150 Combined treatment (n=76) vsulfasalazine treatment (n=79) group.