Intercorrelation data of biochemical serum markers of skeletal muscle and possible determinants in AS patients and controls
| Age (y) | BMI (kg/m2) | Lean body mass (kg) | CRP (mg/l) | Disease duration (y) | |
|---|---|---|---|---|---|
| AS patients (n = 58) | |||||
| CK (IU/l) | −0.09 (0.49) | −0.05 (0.70) | −0.02 (0.89) | −0.48 (< 0.001) | 0.03 (0.82) |
| Aldolase (IU/l) | 0.10 (0.47) | 0.15 (0.26) | 0.14 (0.31) | −0.37 (0.005) | 0.15 (0.26) |
| Creatinine (μmol/l) | 0.45 (<0.001) | 0.26 (0.06) | 0.43 (0.001) | −0.08 (0.56) | −0.22 (0.10) |
| AST (IU/l) | −0.05 (0.72) | −0.11 (0.43) | −0.06 (0.65) | 0.02 (0.86) | 0.01 (0.96) |
| ALT (IU/l) | −0.20 (0.14) | 0.17 (0.19) | 0.34 (0.01) | 0.02 (0.84) | −0.10 (0.45) |
| Disease duration (y) | 0.63 (< 0.001) | −0.17 (0.21) | −0.14 (0.32) | −0.23 (0.09) | — |
| Controls (n = 60) | |||||
| CK (IU/l) | −0.36 (0.006) | 0.29 (0.03) | 0.15 (0.26) | −0.08 (0.56) | — |
| Aldolase (IU/l) | 0.02 (0.88) | 0.27 (0.05) | 0.25 (0.07) | 0.07 (0.62) | — |
| Creatinine (μmol/l) | 0.23 (0.08) | −0.07 (0.60) | −0.21 (0.12) | 0.00 (0.98) | — |
| AST (IU/l) | −0.28 (0.04) | 0.32 (0.02) | 0.32 (0.02) | 0.04 (0.76) | — |
| ALT (IU/l) | −0.10 (0.48) | 0.40 (0.003) | 0.33 (0.01) | 0.09 (0.52) | — |
Values are the partial correlation coefficients (p value), adjusted for age and sex, or adjusted for sex only when correlated with age. The lean body mass is estimated by the formula of Deurenberget al. 19