Shared epitope | Familial RA (n=129) n (%) |
Non-familial RA (n=217) n (%) |
+/+ | 62 (48.1) | 72 (33.2) |
+/− | 43 (33.3) | 97 (44.7) |
−/− | 24 (18.6) | 48 (22.1) |
χ2=7.651 (df=2), p=0.022. +/+ patients homozygous for shared epitope. +/− patients heterozygous for shared epitope. −/− patients negative for shared epitope.