Effect of standing on group average values of heart rate (ratio 30/15; E/I measured supine), slope of the spontaneous baroreflex (SBR), and plasma catecholamines
| E / I | 30 / 15 | Number of spontaneous BR sequences | SBR slope (ms/mm Hg) | noradrenaline (pg/ml) | adrenaline (pg/ml) | dopamine (pg/ml) | |
|---|---|---|---|---|---|---|---|
| Controls | |||||||
| Supine | 1.46 (0.05) | 1.38 (0.05) | 30 (6.6) | 19.7 (3.2)*** | 270 (21) | 49 (6) | 62 (4) |
| Upright | 62 (9.3)*** | 8.8 (1.1) | 557 (38)*** | 78 (13)*** | 62 (3.8) | ||
| AS patients | |||||||
| Supine | 1.39 (0.04) | 1.29 (0.05) | 34 (4.8) | 16.7 (2.8)*** | 262 (17) | 50 (5.5) | 58 (3.6) |
| Upright | 54 (8.9)*** | 5.4 (0.6)§§ | 525 (41)*** | 85 (10)*** | 57 (4.7) | ||
| BASDAI > 5 | 1.37 (0.06) | 1.21 (0.06)2-152 | |||||
| Supine | 35 (6.3) | 15.4 (3.2)*** | 260 (27) | 57 (10) | 57 (5) | ||
| Upright | 49 (12)*** | 4.3 (0.46)§§ | † 580 (62)*** | 101 (21)*** | 57 (8) | ||
| BASDAI < 5 | 1.42 (0.06) | 1.39 (0.09) | |||||
| Supine | 32 (8.8) | 18.4 (5.6)*** | 265 (23) | 41 (7) | 58 (5) | ||
| Upright | 61 (14)*** | 6.9 (1.2) | 447 (47)*** | 70 (13)*** | 58 (5) | ||
| ERS>20 and CRP>20 | 1.37 (0.06) | 1.19 (0.07)2-152 | |||||
| Supine | 31 (7.4) | 12.8 (4.1)*** | 287 (26) | 51 (10) | 53 (6) | ||
| Upright | 42 (13)*** | 4.7 (0.7) § | 540 (75)*** | 84 (22)*** | 54 (9) | ||
| ERS<20 and CRP<20 | 1.41 (0.05) | 1.37 (0.08) | |||||
| Supine | 36 (7.3) | 19.8 (4.1)*** | 240 (24) | 50 (6) | 62 (4.3) | ||
| Upright | 64 (12)*** | 6.03 (1) | 512 (53)*** | 88 (11)*** | 60 (5) | ||
↵2-152 = p<0.05 between these patients and both the control subjects and the other patient groups; * = p<0.05 and *** = p<0.001 between supine and standing; § and §§, respectively for p<0.03 and p<0.01 between patients and control subjects in the standing posture.† = p<0.07 between patients with BASDAI >5 and <5. Data shown as mean (SEM). Abbreviations as in table 1.